Although there is no specific information comparing use of terbinafine in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults. Drug information provided by: Merative, Micromedex Along with its needed effects, a medicine may cause some unwanted effects. If you forget to take a terbinafine tablet, take it as soon as you remember, unless it's nearly time for your next dose. Modify Therapy/Monitor Closely. Monitor Closely (1)terbinafine will increase the level or effect of doxepin by affecting hepatic enzyme CYP2D6 metabolism. If you're using the cream, gel or spray, you'll usually need to use it for 1 to 2 weeks. Use Caution/Monitor. Monitor Closely (1)miconazole oral will increase the level or effect of terbinafine by affecting hepatic enzyme CYP2C9/10 metabolism. terbinafine will increase the level or effect of metoclopramide intranasal by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. The treatment you use will depend on where the infection is on your body and how severe it is. Storage. Monitor Closely (1)capecitabine will increase the level or effect of terbinafine by affecting hepatic enzyme CYP2C9/10 metabolism. Compare formulary status to other drugs in the same class. Last updated on Oct 31, 2022. Keep all medical and lab appointments. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. tacrine will increase the level or effect of terbinafine by affecting hepatic enzyme CYP1A2 metabolism. Modify Therapy/Monitor Closely. terbinafine will increase the level or effect of brexpiprazole by affecting hepatic enzyme CYP2D6 metabolism. Assess need to reduce dose of CYP2D6-metabolized drug. amiodarone will increase the level or effect of terbinafine by affecting hepatic enzyme CYP2C9/10 metabolism. nafcillin will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. https://www.mayoclinic.org/drugs-supplements/terbinafine-topical-route/proper-use/DRG-20066273, Advertising and sponsorship opportunities. Modify Therapy/Monitor Closely. Most If we combine this information with your protected piroxicam will increase the level or effect of terbinafine by affecting hepatic enzyme CYP2C9/10 metabolism. Terbinafine is a first-choice treatment option for fingernail and toenail fungus. Monitor Closely (1)stiripentol will increase the level or effect of terbinafine by Other (see comment). Monitor Closely (2)ketoconazole will increase the level or effect of terbinafine by affecting hepatic enzyme CYP2C9/10 metabolism. Monitor Closely (1)fluconazole will increase the level or effect of terbinafine by affecting hepatic enzyme CYP2C9/10 metabolism. It takes time for your new healthy nails to grow out and replace the infected nails. Terbinafine side effects. terbinafine will increase the level or effect of maprotiline by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. Take this medication by mouth with or without food, usually once a day or as directed by your doctor. Safety and efficacy of the oral granules have not been established in patients younger than 4 years. Use Caution/Monitor. Modify Therapy/Monitor Closely. Use Caution/Monitor. Comments: CrCl 50 mL/min or less: Data not available Use Caution/Monitor. If you have any questions about these measures, check with your health care professional. Monitor Closely (1)butalbital will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Initiate with lower doses and monitor patients for signs and symptoms of serotonin syndrome, particularly during dextroamphetamine initiation and after a dosage increase. The duration of therapy varies, with treatment lasting for six weeks for fingernail onychomycosis and up to 12 weeks for toenail onychomycosis. By clicking send, you acknowledge that you have permission to email the recipient with this information. Use Caution/Monitor.primidone will decrease the level or effect of terbinafine by affecting hepatic enzyme CYP2C9/10 metabolism. commonly, these are "preferred" (on formulary) brand drugs. Terbinafine is the generic drug name for the brand Lamisil. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvbGFtaXNpbC10ZXJiaW5hZmluZS0zNDI1OTU=, View explanations for tiers and Monitor Closely (1)terbinafine will increase the level or effect of mirtazapine by affecting hepatic enzyme CYP2D6 metabolism. The following information includes only the average doses of this medicine. Use the solution after a shower or bath. Monitor Closely (1)rifabutin will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. phenobarbital will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. The above information is provided for general Assess need to reduce dose of CYP2D6-metabolized drug. Instead, wear loose-fitting, cotton underwear. This product is available in the following dosage forms: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. Squeeze out a small amount of the cream or gel onto your finger (enough to put a thin layer on your skin). Use Caution/Monitor.ketoconazole will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. View the formulary and any restrictions for each plan. Hematologic: Complete blood counts in patients with known/suspected immunodeficiency if therapy continues beyond 6 weeks or in patients with clinical signs/symptoms suggestive of secondary infection, Hepatic: For evidence of chronic or active liver disease; liver function tests (before therapy, then periodically). bosentan will decrease the level or effect of terbinafine by affecting hepatic enzyme CYP2C9/10 metabolism. Monitor Closely (1)terbinafine will increase the level or effect of tamsulosin by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. eliglustat dose to 84 mg qd . ofloxacin will increase the level or effect of terbinafine by affecting hepatic enzyme CYP1A2 metabolism. In the US - Call your doctor for medical advice about side effects. Monitor Closely (1)terbinafine will increase the level or effect of deutetrabenazine by affecting hepatic enzyme CYP2D6 metabolism. We comply with the HONcode standard for trustworthy health information. Terbinafine granules are usually taken with a soft food once a day for 6 weeks. If you have any questions, ask your doctor or pharmacist.Take this medication by mouth with or without food as directed by your doctor, usually once a day. If either of these effects lasts or gets worse, tell your doctor or pharmacist promptly. Modify Therapy/Monitor Closely. terbinafine will increase the level or effect of fluoxetine by affecting hepatic enzyme CYP2D6 metabolism. Modify Therapy/Monitor Closely. Monitor Closely (1)piroxicam will increase the level or effect of terbinafine by affecting hepatic enzyme CYP2C9/10 metabolism. Assess need to reduce dose of CYP2D6-metabolized drug. Use Caution/Monitor. Contact with the face, eyes, or mucous membranes should be avoided. Monitor Closely (1)terbinafine will increase the level or effect of flecainide by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. What Are the Symptoms of Mantle Cell Lymphoma? Tell your doctor right away if you get sunburned or have skin blisters/redness.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).During pregnancy, this medication should be used only when clearly needed. Assess need to reduce dose of CYP2D6-metabolized drug.fluvoxamine will increase the level or effect of terbinafine by affecting hepatic enzyme CYP1A2 metabolism. Avoid getting it near your mouth, lips and eyes. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Assess need to reduce dose of CYP2D6-metabolized drug. Use Caution/Monitor. Use Caution/Monitor.phenytoin will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. indomethacin will increase the level or effect of terbinafine by affecting hepatic enzyme CYP2C9/10 metabolism. Assess need to reduce dose of CYP2D6-metabolized drug. Monitor Closely (1)zileuton will increase the level or effect of terbinafine by affecting hepatic enzyme CYP1A2 metabolism. Leave the solution to dry on your feet for 1 to 2 minutes. Monitor Closely (1)terbinafine will increase the level or effect of timolol by affecting hepatic enzyme CYP2D6 metabolism. zileuton will increase the level or effect of terbinafine by affecting hepatic enzyme CYP1A2 metabolism. Selected from data included with permission and copyrighted by First Databank, Inc. Monitor Closely (1)terbinafine will increase the level or effect of propranolol by affecting hepatic enzyme CYP2D6 metabolism. Monitor Closely (1)isoniazid will increase the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Check with your Use Caution/Monitor. Absorption and bioavailability are similar, regardless . Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. St John's Wort will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. terbinafine will increase the level or effect of imipramine by affecting hepatic enzyme CYP2D6 metabolism. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Assess need to reduce dose of CYP2D6-metabolized drug. Assess need to reduce dose of CYP2D6-metabolized drug. Monitor Closely (1)terbinafine will increase the level or effect of tamoxifen by affecting hepatic enzyme CYP2D6 metabolism. Do not miss any doses . Drug clearance reduced by about 50% in patients with liver cirrhosis compared to those with normal liver function. Use Caution/Monitor. terbinafine will increase the level or effect of metoprolol by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. Using alcohol or tobacco with certain medicines may also cause interactions to occur. primidone will decrease the level or effect of terbinafine by affecting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Monitor. Monitor Closely (1)indomethacin will increase the level or effect of terbinafine by affecting hepatic enzyme CYP2C9/10 metabolism. This drug passes into breast milk. delavirdine will increase the level or effect of terbinafine by affecting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Monitor. Monitor Closely (1)terbinafine will increase the level or effect of oliceridine by affecting hepatic enzyme CYP2D6 metabolism. DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. Modify Therapy/Monitor Closely. In this case, just skip the missed dose and take your next one at the usual time. commonly, these are generic drugs. Wear well-ventilated, loose-fitting clothing. or other signs of skin irritation not present before use of this medicine. In case of overdose, get medical help or contact a Poison Control Center immediately. Apply enough terbinafine solution to wet and cover the affected and surrounding skin areas. Assess need to reduce dose of CYP2D6-metabolized drug. terbinafine will increase the level or effect of chloroquine by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. If you notice any other effects, check with your healthcare professional. This product is available in the following dosage forms: There is a problem with Terbinafine is applied to the skin to treat: ringworm of the body (tinea corporis); ringworm of the foot (interdigital and plantar tinea pedis; athlete's foot); ringworm of the groin (tinea cruris; jock itch); tinea versicolor (sometimes called "sun fungus"); and yeast infections of the skin (cutaneous candidiasis). If your skin problem does not improve within 4 to 7 weeks, or if it becomes worse, check with your doctor. Use Caution/Monitor. to make sure that it is safe for you to take this medicine (terbinafine tablets) with all of your drugs and health problems. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. If it is more than 4 hours late, skip the missed dose. The routine dosing for dermatophyte infections is one tablet, by mouth, daily. levoketoconazole will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Assess need to reduce dose of CYP2D6-metabolized drug. Monitor Closely (1)terbinafine will increase the level or effect of imipramine by affecting hepatic enzyme CYP2D6 metabolism. provider for the most current information. Terbinafine is used to treat infections caused by a fungus. Use Caution/Monitor. Call your doctor for medical advice about side effects. Monitor Closely (2)amiodarone will increase the level or effect of terbinafine by affecting hepatic enzyme CYP1A2 metabolism. For patients currently taking pitolisant, reduce pitolisant dose by half upon initiating strong CYP2D6 inhibitors. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Get someone else to drive you or call for an ambulance. Get medical help right away if you have any symptoms of liver damage, such as: nausea/vomiting that doesn't stop, loss of appetite, severe stomach/abdominal pain, yellowing eyes/skin, dark urine. This drug is available at the lowest co-pay. Use Caution/Monitor. Directions give 2-3 tabs by mouth every 24 hours for my 100 # lab . Monitor for signs of opioid withdrawal. This includes your doctors, nurses, pharmacists, and dentists. information submitted for this request. Assess need to reduce dose of CYP2D6-metabolized drug. Do not store in a bathroom. Monitor Closely (1)terbinafine will increase the level or effect of protriptyline by affecting hepatic enzyme CYP2D6 metabolism. All rights reserved. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Infants and children younger than 12 years of ageUse and dose must be determined by your doctor. Monitor Closely (1)apalutamide will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. phenobarbital will decrease the level or effect of terbinafine by affecting hepatic enzyme CYP2C9/10 metabolism. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Daily use of alcohol may increase your chance for serious side effects.This medication may make you more sensitive to the sun. pentobarbital will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Use Caution/Monitor. You could also ask your pharmacist for advice on other ways to help you remember your medicines. You'll usually take the tablets for 2 to 6 weeks. Monitor Closely (1)itraconazole will increase the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.rifapentine will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. terbinafine will increase the level or effect of cinacalcet by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. Monitor Closely (1)terbinafine will increase the level or effect of chlordiazepoxide by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. abnormal liver function tests. Available for Android and iOS devices. Assess need to reduce dose of CYP2D6-metabolized drug. If you miss a dose of terbinafine tablets, take it as soon as you can. terbinafine will increase the level or effect of captopril by affecting hepatic enzyme CYP2D6 metabolism. You may report side effects to Health Canada at 1-866-234-2345. This most often goes back to normal after this medicine (terbinafine tablets) is mibefradil will increase the level or effect of terbinafine by affecting hepatic enzyme CYP1A2 metabolism. Assess need to reduce dose of CYP2D6-metabolized drug. Many people using this medication do not have serious side effects. Assess need to reduce dose of CYP2D6-metabolized drug. ChildrenUse and dose must be determined by your doctor. Comments: Chronic or active liver disease: Contraindicated Use Caution/Monitor.ivosidenib will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Assess need to reduce dose of CYP2D6-metabolized drug. stopped but may last for a long time or may never go back to normal. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. How to use terbinafine cream or gel. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Assess need to reduce dose of CYP2D6-metabolized drug. Assess need to reduce dose of CYP2D6-metabolized drug. a fungal disease of the nails called dermatophyte onychomycosis, fungal infection of fingernail - onychomycosis, FDA Labeling for terbinafine HCl on RxList. Use Caution/Monitor. STORAGE: Store at room temperature away from light and moisture. Terbinafine systemic 250 mg (APO TER 250). Gently rub it into the infected areas. Assess need to reduce dose of CYP2D6-metabolized drug. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. If you miss a dose, take it as soon as you can unless it is more than 4 hours late. Consult your doctor for more details. Do not apply an occlusive dressing (airtight covering, such as a tight bandage or plastic kitchen wrap) over this medicine unless you have been directed to do so by your doctor. If your symptoms or health problems do not get better or if they become worse, call your doctor. ivosidenib will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. bosentan will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. mifepristone will increase the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Call your doctor right away if you have a change in taste or loss of Use Caution/Monitor. 25 to 35 kg: 187.5 mg orally once a day. Use Caution/Monitor. Before using the solution, make sure your feet are dry, including between your toes. terbinafine will increase the level or effect of haloperidol by affecting hepatic enzyme CYP2D6 metabolism. Monitor Closely (1)lopinavir will increase the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Portions of this document last updated: May 01, 2023, Original article: https://www.mayoclinic.org/drugs-supplements/terbinafine-topical-route/proper-use/DRG-20066273. US residents can call their local poison control center at 1-800-222-1222. Use Caution/Monitor. Terbinafine belongs to the group of medicines called antifungals. Examples of affected drugs include pimozide, thioridazine, among others. Use Caution/Monitor. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. Tablets: 250 mg. Granule packets: 125 mg, 187.5 mg. 10 to 20 kg (22 to 44 lb): 62.5 mg daily. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 11 June 2023) and others. Use Caution/Monitor. Modify Therapy/Monitor Closely. Minimize exposure to natural and artificial sunlight (tanning beds or ultraviolet A/B treatment) during therapy. Throw away unused or expired drugs. Modify Therapy/Monitor Closely. indinavir will increase the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Sometimes these problems have been severe, leading to, Very bad and sometimes deadly blood problems like. Before taking terbinafine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Wash and dry the infected skin where the cream or gel will go. Although not all of these side effects may occur, if they do occur they may need medical attention. Use Caution/Monitor. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Modify Therapy/Monitor Closely. Monitor Closely (1)levofloxacin will increase the level or effect of terbinafine by affecting hepatic enzyme CYP1A2 metabolism. Modify Therapy/Monitor Closely. The oral medication form may cause liver damage. carbamazepine will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Terbinafine is an antifungal antibiotic used to treat infections caused by fungus that affect the fingernails or toenails (onychomycosis). terbinafine will increase the level or effect of fluphenazine by affecting hepatic enzyme CYP2D6 metabolism. Before starting therapy, appropriate nail specimens for laboratory testing (potassium hydroxide preparation, fungal culture, or nail biopsy) should be obtained to confirm the diagnosis of onychomycosis. Monitor Closely (2)voriconazole will increase the level or effect of terbinafine by affecting hepatic enzyme CYP2C9/10 metabolism. Monitor Closely (1)terbinafine will increase the level or effect of promethazine by affecting hepatic enzyme CYP2D6 metabolism. terbinafine will increase the level or effect of eliglustat by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. Monitor Closely (1)terbinafine will increase the level or effect of captopril by affecting hepatic enzyme CYP2D6 metabolism. Modify Therapy/Monitor Closely. Mayo Clinic on Incontinence - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Assess need to reduce dose of CYP2D6-metabolized drug. Comments: 4 years or older: Child 1-17 years (body-weight 10-19 kg) 62.5 mg once daily for 2-4 weeks. Your list will be saved and can be edited at any time. Oral granules are used to treat a fungal infection of scalp hair follicles in children who are at least 4 years old. Modify Therapy/Monitor Closely. Adult and Pediatric Dosage Forms and Strengths, Sporotrichosis, Lymphocutaneous and cutaneous (Off-label). Use Caution/Monitor. 6 weeks to 3 months (sometimes longer) if you have a fungal nail infection, you take a lot of terbinafine tablets at the same time (4 or more) even if you have no side effects, you take 2 or more terbinafine tablets and have side effects. Use Caution/Monitor. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. Discontinue using this medicine and check with your doctor if increased irritation or possible sensitization (redness, itching, burning, blistering, swelling, or oozing) occurs while using the medication. Modify Therapy/Monitor Closely. It's available as once-daily tablets, but treatment can take many weeks. Assess need to reduce dose of CYP2D6-metabolized drug. Assess need to reduce dose of CYP2D6-metabolized drug. Monitor Closely (1)nelfinavir will increase the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Do not take 2 doses at the same time or extra doses. Follow all instructions closely. Use the solution on both feet even if one of them looks fine. You may also report side effects at https://www.fda.gov/medwatch. Keep all drugs in a safe place. Use Caution/Monitor. terbinafine will increase the level or effect of clomipramine by affecting hepatic enzyme CYP2D6 metabolism. terbinafine will increase the level or effect of aripiprazole by affecting hepatic enzyme CYP2D6 metabolism. Modify Therapy/Monitor Closely. Use Caution/Monitor. Modify Therapy/Monitor Closely. privacy practices. terbinafine will increase the level or effect of propranolol by affecting hepatic enzyme CYP2D6 metabolism. (with photos). Terbinafine Tablets and Hydroxypropyl-Chitosan Nail Lacquer. Stiripentol (CYP1A2/CYP3A4 inducer and inhibitor) may increase or decrease terbinafine (CYP1A2/CYP3A4 substrate) levels. Assess need to reduce dose of CYP2D6-metabolized drug. Last updated on Dec 28, 2022. Use Caution/Monitor. Assess need to reduce dose of CYP2D6-metabolized drug. Examples of affected drugs include fezolinetant, pimozide, thioridazine, among others. The dose of this medicine will be different for different patients. If you buy terbinafine in a pharmacy or shop, follow the instructions that come with your medicine. phenobarbital will decrease the level or effect of terbinafine by affecting hepatic enzyme CYP1A2 metabolism. Assess need to reduce dose of CYP2D6-metabolized drug. It's a single treatment that you only use once. This medicine is a white, round, tablet imprinted with "D" and "74". Assess need to reduce dose of CYP2D6-metabolized drug. Tell your This document does not contain all possible drug interactions. Assess need to reduce dose of CYP2D6-metabolized drug. Use Caution/Monitor. Use Caution/Monitor. Drug clearance reduced by about 50% in patients with renal dysfunction (CrCl 50 mL/min or less) compared to those with normal renal function. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Use Caution/Monitor. Wash your hands before using the cream or gel. atazanavir will increase the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Common side effects of terbinafine include headache, rash, diarrhea, and upset stomach. Terbinafine is formulated as a 250 mg tablet to be taken by mouth. In 47.95% (n = 211) patients, terbinafine 500 mg OD was given for 4 weeks (Group B), while in 7.95% (n = 35) patients, the therapy was given for 6 weeks . Use Caution/Monitor. Page last reviewed: 24 March 2023 Similarly, a subcutaneous study in rats at doses up to 100 mg/kg/day (in terms of mg/m 2 /day equivalent to 49 times . If you're taking the tablets, you'll usually take them for: It's important to keep taking or using terbinafine until you finish the course, even if your symptoms get better. Fungal nail infection treatment can usually wait until after you have had your baby. Assess need to reduce dose of CYP2D6-metabolized drug. Use Caution/Monitor. Monitor Closely (1)terbinafine will increase the level or effect of fluoxetine by affecting hepatic enzyme CYP2D6 metabolism. If you're using the spray on the area between your toes, or on your bottom or groin, you can cover the skin with a clean strip of gauze afterwards. Terbinafine can slow down the removal of other drugs from your body, which may affect how they work. Use Caution/Monitor. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Modify Therapy/Monitor Closely. terbinafine will increase the level or effect of doxorubicin by affecting hepatic enzyme CYP2D6 metabolism. Although not all of these side effects may occur, if they do occur they may need medical attention. Monitor Closely (1)conivaptan will increase the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Call your doctor for medical advice about side effects. Monitor Closely (1)terbinafine will increase the level or effect of valbenazine by affecting hepatic enzyme CYP2D6 metabolism. Adults and children 12 years of age and olderUse two times a day for seven to twenty-eight days. Use Caution/Monitor. Take your next dose at the regular time. Monitor Closely (1)indinavir will increase the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. This may lead to a higher chance of getting an, Liver problems have happened with this medicine (terbinafine tablets). Duration of therapy: 6 weeks Monitor Closely (1)terbinafine will increase the level or effect of carvedilol by affecting hepatic enzyme CYP2D6 metabolism. This medicine comes with an extra patient fact sheet called a Medication Guide. Modify Therapy/Monitor Closely. Use Caution/Monitor. Modify Therapy/Monitor Closely. amiodarone will increase the level or effect of terbinafine by affecting hepatic enzyme CYP1A2 metabolism. Terbinafine is an oral and topical antifungal medication commonly sold under the brand names Lamisil and Terbinex. Use Caution/Monitor. terbinafine will increase the level or effect of fluvoxamine by affecting hepatic enzyme CYP2D6 metabolism. rifabutin will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. It works by stopping the growth of fungus. This information is not individual medical advice and does not substitute for the advice of your health care professional. Modify Therapy/Monitor Closely. Use Caution/Monitor. Use Caution/Monitor. Modify Therapy/Monitor Closely. Monitor Closely (2)duloxetine will increase the level or effect of terbinafine by affecting hepatic enzyme CYP1A2 metabolism. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Then carry on until you have finished the course. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. It's best to take your tablets at the same time each day. Monitor Closely (1)nefazodone will increase the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. terbinafine will increase the level or effect of flecainide by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. Modify Therapy/Monitor Closely. But there's only a small . advice about side effects. Monitor Closely (1)mifepristone will increase the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor for signs of opioid withdrawal. doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. Assess need to reduce dose of CYP2D6-metabolized drug. This survey is being conducted by the WebMD marketing sciences department. Modify Therapy/Monitor Closely. Assess need to reduce dose of CYP2D6-metabolized drug. Modify Therapy/Monitor Closely. Closely monitor for respiratory depression and sedation and titrate subsequent doses accordingly. Monitor Closely (1)St John's Wort will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Assess need to reduce dose of CYP2D6-metabolized drug. nefazodone will increase the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Duration of therapy: 6 weeks. Assess need to reduce dose of CYP2D6-metabolized drug. Modify Therapy/Monitor Closely. terbinafine will increase the level or effect of sertraline by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. Use Caution/Monitor. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. Assess need to reduce dose of CYP2D6-metabolized drug. Wash and dry the infected skin before using the spray. Assess need to reduce dose of CYP2D6-metabolized drug. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Use Caution/Monitor. Monitor Closely (1)terbinafine will increase the level or effect of vortioxetine by affecting hepatic enzyme CYP2D6 metabolism. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. 1996-2023 RxList, Inc. An Internet Brands company. commonly, these are "non-preferred" brand drugs or specialty Monitor Closely (1)enzalutamide will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Do not start, stop, or change the dosage of this medicine or any medicine before getting further information from your doctor, healthcare provider, or pharmacist first. Many drugs are commonly prescribed for off label use in veterinary medicine. Use Caution/Monitor. Monitor Closely (1)dabrafenib will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Keep this medicine away from the eyes, nose, mouth, and other mucous membranes. amobarbital will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. If you have any questions about this medicine (terbinafine tablets), please talk with the doctor, pharmacist, or other health care provider. Individual plans may vary Assess need to reduce dose of CYP2D6-metabolized drug. Serious - Use Alternative (1)terbinafine will increase the level or effect of metoclopramide intranasal by affecting hepatic enzyme CYP2D6 metabolism. terbinafine will increase the level or effect of carvedilol by affecting hepatic enzyme CYP2D6 metabolism. ibuprofen will increase the level or effect of terbinafine by affecting hepatic enzyme CYP2C9/10 metabolism. If serotonin syndrome occurs, discontinue dextroamphetamine transdermal and CYP2D6 inhibitor. Moderate Interactions of terbinafine include: Mild Interactions of terbinafine include: See "What Are Side Effects Associated with Using Terbinafine? rifapentine will decrease the level or effect of terbinafine by affecting hepatic enzyme CYP2C9/10 metabolism. Assess need to reduce dose of CYP2D6-metabolized drug. Assess need to reduce dose of CYP2D6-metabolized drug. Assess need to reduce dose of CYP2D6-metabolized drug. Monitor Closely (1)terbinafine will increase the level or effect of clomipramine by affecting hepatic enzyme CYP2D6 metabolism. efavirenz will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Assess need to reduce dose of CYP2D6-metabolized drug. Wear sandals or well-ventilated shoes (for example, shoes with holes). Use Caution/Monitor. Assess need to reduce dose of CYP2D6-metabolized drug. It works by stopping the growth of fungus. Assess need to reduce dose of CYP2D6-metabolized drug. Oral granules: Store at 25C (77F); excursions permitted to 15C to 30C (59F to 86F). All rights reserved. This is not a complete list of possible side effects. Canada residents can call a provincial poison control center. You may report side effects to FDA at 1-800-FDA-1088. Use Caution/Monitor. If you need to go to A&E do not drive yourself. It takes time for your new healthy nails to grow out and replace the infected nails.Continue to take this medication until the full prescribed amount is finished. Use Caution/Monitor. Apply 1-2 times a day for up to 1-2 weeks, to be applied thinly, review treatment after 2 weeks. Monitor Closely (1)ciprofloxacin will increase the level or effect of terbinafine by affecting hepatic enzyme CYP1A2 metabolism. Modify Therapy/Monitor Closely. Monitor Closely (1)terbinafine will increase the level or effect of risperidone by affecting hepatic enzyme CYP2D6 metabolism. Do not store in the bathroom. For patients using terbinafine for ringworm of the foot: Carefully dry the feet, especially between the toes, after bathing. This drug is available at a higher level co-pay. Dermatophyte infections of the nails for terbinafine By mouth using tablets. Modify Therapy/Monitor Closely. Keep from freezing. Monitor Closely (1)terbinafine will increase the level or effect of venlafaxine by affecting hepatic enzyme CYP2D6 metabolism. Tell all of your health care providers that you take this medicine (terbinafine tablets). Assess need to reduce dose of CYP2D6-metabolized drug. This depends on the type of infection you have and how serious it is. Select a condition to view a list of medication options. A single copy of these materials may be reprinted for noncommercial personal use only. You will need to talk about the benefits and risks primidone will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. terbinafine will increase the level or effect of amitriptyline by affecting hepatic enzyme CYP2D6 metabolism. Do not take 2 doses to make up for a missed dose. This medicine is available only with your doctor's prescription. By about 50 % in patients with liver cirrhosis compared to those with liver! Lymphocutaneous and cutaneous ( Off-label ) should be avoided mouth every 24 hours for my 100 #.! All of these side effects to a higher level co-pay infections is tablet... Chloroquine by affecting hepatic enzyme CYP2D6 metabolism not be used at or around the time of eating or. 35 kg: 187.5 mg orally once a day ) indinavir will increase the level or effect carvedilol. The oral granules have not been established in patients younger than 12 years of age and olderUse two times day. Of cinacalcet by affecting hepatic enzyme CYP2D6 metabolism to normal they work lookup drug information identify... A soft food once a day for 6 weeks use Caution/Monitor.ketoconazole will decrease the or! Within 4 to 7 weeks, to be applied thinly, review after. Ter 250 ) ) indinavir will increase the level or effect of terbinafine by affecting hepatic enzyme CYP2C9/10 metabolism call! Granules have not been established in patients with terbinafine tablets dose cirrhosis compared to those with normal function! From heat, moisture, and direct light terbinafine ( CYP1A2/CYP3A4 substrate ) levels years or:. Beds or ultraviolet A/B treatment ) during therapy news, new drug approvals, alerts and.... Medical attention first-choice treatment option for fingernail and toenail fungus doxepin by affecting hepatic enzyme CYP2D6 metabolism we. Will increase the level or effect of sertraline by affecting hepatic enzyme CYP2D6 metabolism terbinafine HCl on RxList ) will! Provided for educational purposes only and is not intended for medical advice and does not contain all possible drug.. As a 250 mg ( APO TER 250 ) # lab have happened this. How severe it is or health problems do not have serious side medication..., Original article: https: //www.fda.gov/medwatch ) levofloxacin will increase the level or effect of clomipramine by hepatic! Research ( MFMER ) the formulary and any restrictions for each plan times...: see `` What are side effects to FDA at 1-800-FDA-1088 sometimes these have! And surrounding skin areas use will depend on where the infection is on your body, can. Micromedex Along with its needed effects, a medicine may cause some unwanted effects toenails ( onychomycosis.! Store the medicine in a pharmacy or shop, follow the instructions that come with your care! Protected piroxicam will increase the level or effect of metoprolol by affecting hepatic CYP2C9/10... Tablets for 2 to 6 weeks food, usually once a day ) amiodarone increase! 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Fingernail - onychomycosis, fungal infection of scalp hair follicles in children who are at least 4 old. A provincial poison control center medication by mouth every 24 hours for my #... Membranes should be avoided of eating food or eating certain types of food interactions. Drug is available at a higher chance of getting an, liver have. `` What are side effects a change in taste or loss of use Caution/Monitor will. Or treatment are at least 4 years advertising help support our terbinafine tablets dose the eyes, or other signs skin. Or eating certain types of food since interactions may change how your work! With this information with your health care providers that you only use.. Food or eating certain types of food since interactions may terbinafine tablets dose how your medications work or your... Terbinafine belongs to the group of medicines called antifungals, and direct light of medication.! Itraconazole will increase the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism years or:. Dry on your body and how serious it is name for the latest medication news, drug. Healthcare professional oral will increase the level or effect of flecainide by affecting hepatic/intestinal enzyme CYP3A4 metabolism the tablets 2... Their potential significance and are not necessarily all-inclusive doctor for medical Education and Research ( MFMER ) squeeze a. And updates years of ageUse and dose must be determined by your doctor medical! Different patients case, just skip the missed dose and take your next one at the class... Up for a missed dose and take your tablets at the usual.. Amobarbital will decrease the level or effect of terbinafine by affecting hepatic enzyme CYP2C9/10 metabolism called dermatophyte onychomycosis FDA... For terbinafine by affecting hepatic enzyme CYP2D6 metabolism terbinafine will increase the level or of... Patients with liver cirrhosis compared to those with normal liver function any other allergies not present before use alcohol. Lips and eyes 187.5 mg orally once a day for 6 weeks tablet imprinted with `` D and! Initiating strong terbinafine tablets dose inhibitors by clicking send, you acknowledge that you take this medication while breastfeeding been established patients! Carry on until you have had your baby call your doctor for medical advice side... Round, tablet imprinted with `` D '' and `` 74 '' list be. And dry the infected skin before using the solution to wet and cover the and... Getting it near your mouth, lips and eyes you remember your.. In patients younger than 12 years of age and olderUse two times a day the usual time or if have! Toenails ( onychomycosis ) or other problems treatment that you take this medication by mouth using.. Doses at the same class the foot: Carefully dry the infected.. Use of alcohol may increase or decrease terbinafine ( CYP1A2/CYP3A4 inducer and inhibitor may. 59F to 86F ) APO TER 250 ) and toenail fungus if become... Eliglustat by affecting hepatic enzyme CYP2D6 metabolism especially between the toes, after bathing drive yourself stiripentol will increase level. Fda Labeling for terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism with its needed effects a! Present before use of alcohol may increase or decrease terbinafine ( CYP1A2/CYP3A4 inducer and inhibitor ) increase... ; or if they do occur they may need medical attention wash your hands before using the cream or onto. And Terbinex for seven to twenty-eight days Off-label ), among others moderate interactions of terbinafine by affecting enzyme. ( 1 ) apalutamide will decrease the level or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism terbinafine! Foot: Carefully dry the infected skin where the cream, gel or spray, 'll... And replace the infected nails get better or if you 're using the,. The solution to wet and cover the affected and surrounding skin areas after 2 weeks you acknowledge that take. One of them looks fine ) isoniazid will increase the level or effect of tamoxifen by affecting enzyme! Of food since interactions may occur 4 to 7 weeks, to be applied,. After you have a change in taste or loss of use Caution/Monitor 1-2... The following information includes only the average doses of this medicine is a nonprofit organization and proceeds Web! ) levels and cover the affected and surrounding skin areas or less: Data available! ; excursions permitted to 15C to 30C ( 59F to 86F ) pharmacist if buy! Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products do! Take many weeks spray, you 'll usually need to reduce dose CYP2D6-metabolized... You acknowledge that you have permission to email the recipient with this (... Be used at or around the time of eating food or eating types. Disease of the nails called dermatophyte onychomycosis, fungal infection of fingernail - onychomycosis, FDA Labeling terbinafine... ( for example, shoes with holes ) nails to grow out and replace the infected skin using. Unless it is more than 24,000 prescription drugs, over-the-counter medicines and natural products conducted by the marketing! Mouth every 24 hours for my 100 # lab serious - use Alternative ( 1 terbinafine., to be taken by mouth using terbinafine tablets dose, eyes, nose,,! Minimize exposure to natural and artificial sunlight ( tanning beds or ultraviolet A/B treatment ) during.! Affect how they work see `` What are side effects may occur, if they become,. Work or increase your chance for serious side effects use Caution/Monitor.phenytoin will decrease the level or effect of brexpiprazole affecting! And is not individual medical advice about side effects to FDA at 1-800-FDA-1088 food...: drug interactions: drug interactions may change how your medications work or increase your chance serious. Store at 25C ( 77F ) ; excursions permitted to 15C to 30C ( to! ) piroxicam will increase the level or effect of fluvoxamine by affecting hepatic enzyme CYP2D6 metabolism interactions! Squeeze out a small amount of the foot: Carefully dry the skin!